Building Software for Biologists with Dr. Vega Shah (Benchling)
Dr. Vega Shah was was like a gold miner during her undergraduate and graduate school studies, except instead of panning for gold, she was searching the metagenomes of ocean samples for new life and new metabolic functions. What she found was a new species of ocean bacteria, but she also realized that the software tools she relied on and the databases she used to answer her research questions were anything but solid. After grad school, she shifted her career to building software for biologists at Dotmatics, integrating tools such as Prism into electronic lab notebooks. Today she’s a program manager at Benchling working to integrate new functions and communicate these resources to scientists everywhere. It's a thoughtful conversation you won't want to miss. Subscribe wherever you listen to podcasts: https://rss.com/podcasts/ladyscientistpodcast/ Links for Vega Shah: LinkedIn: https://www.linkedin.com/in/vegashah/ Twitter: https://twitter.com/dr_alphalyrae The Aliquot (her Substack): https://thealiquot.substack.com/ This episode is sponsored by LabDAO. Check out PLEX, an open source platform for running many of the latest and greatest new computational biology tools including DiffDock, RfDiffusion, and ColabFold. https://labdao.xyz/
Biotech Platform and Product with Dr. Erandi De Silva, Co-Founder Forge Biologics
Scientist & entrepreneur, Dr. Erandi De Silva, grew up in the small country of Botswana, where she lived through an HIV epidemic. Seeing scientists and epidemiologists having a direct translational impact on public health inspired her to pursue a career in science. She immigrated to the US to go to college, and went on to get her PhD and did an industry postdoc at Genentech before founding Forge Biologics. In this episode, we discuss what it's like running a company that has both a 'platform' in the sense that they are a CDMO - they make AAV products for other companies, and a 'product'; they also have a clinical product they are evaluating. Erandi De Silva on LinkedIn: https://www.linkedin.com/in/erandi-de-silva-phd-08076222/ Forge Biologics: https://www.forgebiologics.com/ Leave us a comment if you enjoyed this episode. Subscribe wherever you listen to podcasts.
De-Extinction, Patient Advocacy, and Journey To The C Suite With Claire Aldridge and Emily McGinnis
In this episode of Lady Scientist Podcast, Dr. Jocelynn Pearl hosts Emily McGinnis, Chief of Patient Advocacy at Taysha Gene Therapies, and Claire Aldridge, Chief Strategy Officer at Form Bio (spun out of Colossal Biosciences - the company that wants to de-extinct the dodo bird!) Together, we discuss challenges and advancements in gene therapy for rare diseases, emphasizing patient advocacy in drug development, and the need for optimization and scaling. Emily and Claire share their career journeys to the C Suite. They also recommend resources and organizations for patients seeking information on potential therapies. This episode provides valuable insights into gene therapy, patient advocacy, and the career journeys to the C Suite.
Dr. Madeleine Oudin - Cancer & Neuroscience Researcher, Rare Disease Mom
Dr. Madeleine Oudin knew she was interested in medicine and biology from a young age. She took a science track of courses in high school in France and went on to do her undergraduate studies at McGill University. Despite a lack of advising, she found that she loved research and continued on to get a Masters and PhD in neuroscience. She shifted gears in her postdoc, studying cancer and tumor biology, and was surprised to learn of some of the overlaps with studying neuroscience. These two fields merged to form her research niche when she founded her own lab at Tufts University. But her research focus would shift once again after she discovered the diagnosis of her daughter Margot, who suffers from a rare form of epilepsy caused by gene mutations in SCN8. Together with her husband, she now also studies these types of disorders in mice and is working towards a cure for her daughter. Join us on this episode of LSP to learn from Dr. Oudin's impressive career journey and her inspiring dedication to help her daughter. Guest links: LinkedIn: https://www.linkedin.com/in/madeleine-oudin-56769529/ Twitter: https://twitter.com/MadeleineOudin Donate to Epilepsy Research: https://give.tufts.edu/campaigns/22193/donations/new?designation=scn8aepilepsyresearchfund Subscribe to our show wherever you listen to podcasts! Thank you for listening.
Crash Course in Yeast Chromatin with Dr. Christine Cucinotta
Today we’re joined by another awesome scientist, Dr. Christine Cucinotta. Christine studies gene regulation in yeast in her postdoctoral studies in the Tsukiyama Lab at the Fred Hutch. She also organizes Fragile Nucleosome, a Discord community of scientists and researchers that puts on a seminar series (available to watch on YouTube). We chat about the importance of community in science and what she considers to be groundbreaking work in the field of gene regulation in the last decade. We also get into how she felt about the recent eLife decision to publish preprints (hint - she’s a fan of change!) and the importance of open science! Christine’s Twitter: https://twitter.com/chrstn_eFragile Nucleosome: https://twitter.com/FNucleosome Subscribe to LSP wherever you listen to podcasts. Thanks for listening!