Can sildenafil reduce Alzheimer’s risk, and what does the research show in Europe?

Sildenafil and Alzheimer’s explained: PDE5 inhibition, cerebral blood flow, observational data, dementia risk, and clinical interpretation.

In this episode, we examine studies suggesting a possible association between sildenafil use and reduced Alzheimer’s risk, and how doctors interpret these findings under EU medical guidance.

You’ll learn:

• What sildenafil is (a phosphodiesterase type 5 inhibitor)

• How PDE5 inhibitors affect nitric oxide signalling and blood flow

• The difference between observational associations and proven prevention

• Why improved vascular health may influence cognitive outcomes

• Current limitations of available studies

• Why sildenafil is not prescribed to p ...