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The Journal Club

The Journal Club

by Beimnet Kassaye

New brain cells and how they join the old

In this episode, I cover a paper by Kochan et al., 2024. The title of the paper is "Enhanced mitochondrial fusion during a critical period of synaptic plasticity in adult-born neurons ." Here is the link for the paper https://pubmed.ncbi.nlm.nih.gov/38582081/ Here is the webpage of the Bergami lab: https://bergami-lab.com. You may access other publications and the current focuses of their lab by following the link.

#18 Housekeeping in the schizophrenic brain with Katy Bjornson

Katy shares one of her graduate school papers on how a cell clean-up mechanism improves cognition and its consequences in schizophrenia. Here is a link to the paper: https://pubmed.ncbi.nlm.nih.gov/39019008/ And here is the Cahill lab https://cahilllab.wiscweb.wisc.edu

#17 The brain where it is not "thinking": regulating the immune response

In this episode, I cover a paper by Jin et al., 2024. The title of the paper is "A body-brain circuit that regulates body inflammatory responses ." Here is the link for the paper https://pubmed.ncbi.nlm.nih.gov/38692285/. Here is the webpage of the Kaeser lab: https://www.zukerlab.com. You may access other publications and the current focuses of their lab by following the link.

#16 Dopamine in psychosis and substance use disorder with Loren Peeters

Loren Peeters shares her graduate paper titled Effects of positive mGlu5 modulation on D2 signaling and nicotine-conditioned place preference: Mechanisms of epigenetic inheritance in a transgenerational model of drug abuse vulnerability in psychosis. Here is the link for the paper https://pubmed.ncbi.nlm.nih.gov/39462877/. You can follow the full-text links. Here is the webpage of the Brown lab at East Tennessee State University: https://brownlabetsu.weebly.com You may access other publications and the current focuses of their lab by following the link.

#15 Dopamine as we move and pursue

In this episode, I cover a paper by Cai et al., 2024. The title of the paper is "Dopamine dynamics are dispensable for movement but promote reward responses ." Here is the link for the paper https://www.nature.com/articles/s41586-024-08038-z.epdf?sharing_token=iaTQaNGlwJ3U0t63gRdvoNRgN0jAjWel9jnR3ZoTv0MqwcJmJFCUL7uZ_15TPCZ8espe7y0UtGVKs-OYDW0-m_RyOV3e_4j76PM8ppXJi_A_Epvvz9vVyfGlJxd6RlTQ6xjr5ibCAnzJu4zd5TWqCcvRdGOeu2w-VcIdKNtclgQ%3D. Here is the webpage of the Kaeser lab: https://kaeser.hms.harvard.edu. You may access other publications and the current focuses of their lab by following the link.

# 14 Length of daylight alters potassium channel expression in our serotonin neurons

In this episode, I cover a paper by Giannoni-Guzman et al., 2020. The title of the paper is "Circadian photoperiod alters TREK-1 channel function and expression in dorsal raphe serotonergic neurons via melatonin receptor 1 signaling ." Here is the PubMed link for the article https://pubmed.ncbi.nlm.nih.gov/33210730/. You may access the paper by clicking on the icons under the "Full Text Links" tab. Here is the webpage of the McMahon lab: https://www.mcmahonlab.org. You may access other publications and the current focuses of their lab by following the links. The music for this podcast was composed by Marko Krtinic, and if you would like to check out his work and support him, please visit his Spotify account at https://open.spotify.com/artist/6bJaFvgKIirKMoox9cGHWC?si=_Ou5UC-BRXebl_S7AH-kGg.

#13 Length of daylight and positive mood: the serotonin story

In this episode, I cover a paper by Green et al., 2015. The title of the paper is "Photoperiod Programs Dorsal Raphe Serotonergic Neurons and Affective Behaviors." Here is the PubMed link for the article https://pubmed.ncbi.nlm.nih.gov/25959961/. You may access the paper by clicking on the icons under the "Full Text Links" tab. Here are the webpages of Dr. McMahon and Dr. Grueter respectively: https://www.mcmahonlab.org and https://www.vumc.org/grueter-lab/welcome-grueter-lab. You may access other publications and the current focuses of their lab by following the links. The music for this podcast was composed by Marko Krtinic, and if you would like to check out his work and support him, please visit his Spotify account at https://open.spotify.com/artist/6bJaFvgKIirKMoox9cGHWC?si=_Ou5UC-BRXebl_S7AH-kGg.

#12 Seasonal change in daylight on reward and motivation: the dopamine story

In this episode, I cover a paper by Jameson et al., 2023. The title of the paper is "Photoperiod Impacts Nucleus Accumbens Dopamine Dynamics." Here is the PubMed link for the article https://pubmed.ncbi.nlm.nih.gov/36781229/. You may access the paper by clicking on the icons under the "Full Text Links" tab. Here are the webpages of Dr. McMahon and Dr. Grueter respectively: https://www.mcmahonlab.org and https://www.vumc.org/grueter-lab/welcome-grueter-lab. You may access other publications and the current focuses of their lab by following the links. The music for this podcast was composed by Marko Krtinic, and if you would like to check out his work and support him, please visit his Spotify account at https://open.spotify.com/artist/6bJaFvgKIirKMoox9cGHWC?si=_Ou5UC-BRXebl_S7AH-kGg.

#11 Could KLOTHO be the long-awaited Alzheimer's drug?

In this episode, I cover a paper by Zhao et al., 2020. The title of the paper is "Klotho overexpression improves amyloid-β clearance and cognition in the APP/PS1 mouse model of Alzheimer's disease." Here is the PubMed link for the article https://pubmed.ncbi.nlm.nih.gov/32964663/. You may access the paper by clicking on the icons under the "Full Text Links" tab. Here is the webpage of Dr. Jun-Rong Du: https://www.scu.edu.cn/medical/info/1015/1030.htm You may access other publications and the current focuses of their lab by following the links. The music for this podcast was composed by Marko Krtinic, and if you would like to check out his work and support him, please visit his Spotify account at https://open.spotify.com/artist/6bJaFvgKIirKMoox9cGHWC?si=_Ou5UC-BRXebl_S7AH-kGg.

#10 The Western diet and Alzheimer's disease (Second half with Stedman Stephens)

In this episode, Stedman and I cover the second half of a paper by Poxleitner et al., 2024. The title of the paper is "Western diet increases brain metabolism and adaptive immune responses in a mouse model of amyloidosis." Here is the PubMed link for the article https://pubmed.ncbi.nlm.nih.gov/38745337/. You may access the paper by clicking on the icons under the "Full Text Links" tab. Here are the webpages of Dr. Herfert and Dr. Beziere respectively: http://www.isct.uni-tuebingen.de/wsic/research/research-groups/neurology/functional-and-metabolic-brain-imaging http://www.isct.uni-tuebingen.de/wsic/research/research-groups/immunology-inflammation/inflammation You may access other publications and the current focuses of their lab by following the links. The music for this podcast was composed by Marko Krtinic, and if you would like to check out his work and support him, please visit his Spotify account at https://open.spotify.com/artist/6bJaFvgKIirKMoox9cGHWC?si=_Ou5UC-BRXebl_S7AH-kGg.

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