Rethinking Polycystic Ovary Syndrome. PCOS. Is PCOS an Epiphenomenon

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Episode notes

PCOS is an Epiphenomenon

Polycystic Ovary Syndrome (PCOS), the commonest endocrine disorder in women, affects fertility, metabolism, & quality of life. It is portrayed as a primary disease of the ovaries, where follicles do not mature, ovulation becomes irregular, & multiple cysts appear on ultrasound. Is this the full story?

Our research over the past decade challenges this traditional view. We asked a simple question: Is PCOS the problem, or is it a downstream effect — an epiphenomenon — of something deeper?

Weight Gain Comes First

In our retrospective study of over 170 women with infertility, we noticed that more than 97% of women with PCOS had gained at least 4-5% of their body weight after adolescence before developing PCOS symptoms.

This weight gain was not l ... 

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