Delve into the critical world of preclinical toxicology studies, the essential stepping stone before a new drug can even be considered for human trials. These studies, encompassing acute, subchronic, and chronic designs, are the bedrock of ensuring drug safety, identifying potential hazards early on. We'll explore how scientists use these studies to evaluate a drug's safety profile, examining the different study designs and their specific focuses. We'll also unpack the crucial endpoints examined in these studies, from organ function to behavioral changes, to get a comprehensive understanding of a drug's impact on the body. This episode also sheds light on the strict regulations governing these studies, ensuring both the reliability of the data and the ethical treatment of animals.

Join us as we navigate the ethical considerations surroundin ...