Note sull'episodio
In our episode on addiction, we admitted we weren’t sure if marijuana was truly addictive. That question stuck with me—so I went back to the research.
In this bonus episode, Zane dives into what he found after reviewing two major studies: a 2024 Journal of Clinical Investigation review by Le Foll et al. and a 2025 JAMA Network Open paper by Gowin et al. The evidence? Cannabis can be addictive for some people, and heavy or frequent use is linked to measurable changes in brain circuits that regulate memory, motivation, and control.
We break down how THC affects the endocannabinoid system, why today’s high-potency products raise the risk of dependence, and what brain imaging is revealing about long-term cannabis use. Zane also highlights current treatments for Cannabis Use Disorder (CUD)—from behavioral therapi ...