Primer on Protein Folding (Kessel & Ben-Tal)

Primer on protein structure, function, and motion, covering fundamental concepts in molecular biophysics and bioinformatics. It details the physicochemical properties of proteins, including amino acid structure, secondary and tertiary folding, and the driving forces behind protein stability such as the hydrophobic effect and van der Waals interactions. Significant sections focus on membrane-bound proteins and their unique environment in the lipid bilayer, as well as the intricate mechanisms of protein-ligand and protein-protein interactions, including allostery and its implications for drug design. Furthermore, the text explores enzymatic catalysis, outlining classification systems, reaction kinetics (like Michaelis-Menten), and  ...