Episode 25 - Recent Progress in NF1-PN: Pathophysiology, Role of MEK Inhibitors, Recognizing the NF1-PN Patient

This activity will inform participants about the complex pathophysiology of NF1-PN and how an understanding of molecular pathways has led to the development of MEK inhibitors. The key published and ongoing clinical evidence on the utility of approved and emerging therapies for NF1-PN will be detailed to provide a strong foundation for clinical decision-making. An in-depth guide to recognize and diagnose patients with NF1-PN will also be discussed in this module to facilitate an accurate and timely diagnosis. Overall, this presentation will ensure that participants appreciate the need to recognize and treat NF1-PN among pediatric patients.

Launch Date/Release Date: October 6, 2025

Expiration Date: September 30, 2026

FACULTY

Amy Armstrong, MD

Assistant Professor of Pediatrics

Division of Hematology/ ...