San Francisco 49ers' devastating 35-10 loss to the Buffalo Bills. Christian McCaffrey's season-ending knee injury

Summary

Multiple sources detail the San Francisco 49ers' devastating 35-10 loss to the Buffalo Bills. The game was marked by Christian McCaffrey's potential season-ending knee injury, impacting the team's already injury-plagued season. The 49ers' poor performance, particularly their struggling defense, led to an overall failing grade. Amidst the team's struggles, backup running back Jordan Mason's strong performance has drawn attention from other NFL teams, potentially leading to his departure from San Francisco. Josh Allen's exceptional performance for the Bills further highlighted the 49ers' defeat.