The video compares Arthrosamid® with traditional intra-articular treatments such as corticosteroids and hyaluronic acid, highlighting its non-biodegradable hydrogel structure, synovial coating properties, and its role in reducing inflammatory flare-ups associated with osteoarthritis. We also discuss patient selection, expected duration of effect (2–3 years), cost considerations, and where Arthrosamid® may sit within the conservative-to-surgical treatment pathway for knee OA.