File #004: Paramedics, Pipelines & Phase 4: Doug Schantz on Steering Global Clinical Ops

Veteran clinical-operations leader Doug Schantz joins Clinical Trial Files to trace a career that spans emergency-room stretchers and first-in-human gene-therapy trials. In this lively conversation Doug unpacks:

• how a paramedic’s mindset shaped his approach to Phase 1-4 global programs at Pfizer, AstraZeneca, Alexion, and AskBio;
• the biggest headaches—and hidden advantages—of running studies across borders and therapy areas (oncology, neuroscience, cardiovascular, rare disease, gene therapy);
• practical lessons on in-house vs. outsourced monitoring, risk-based quality management, and building site relationships that last;
• the future of gene-therapy trials—and the three traits he’d engineer into a “perfect” clinical site;

Whether you’re running your first study or steering an  ...