From the Spectrum: Finding Superpowers with Autism

Episodi del podcast

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  Tryptophan, Microtubulus, & Mitosis

  Tryptophan, Microtubulus, & Mitosis

  E61

  14 Aprile, 2025

  38:05

  This episode explores the critical role of tryptophan, an aromatic amino acid, in forming tubulin—the key protein building microtubules, which act as cellular "train tracks" for structure and movement. We delve into how microtubules drive mitosis, the process of cell division essential for growth and repair, and discuss tryptophan’s unique biochemical significance, including its single codon (UGG) and contributions to DNA methylation. We connect these cellular mechanisms to Autism, examining how microtubule disruptions may affect neuron proliferation and migration during prenatal development, potentially leading to sensory processing issues and altered connectivity. The episode highlights the intricate dance of cells in neural tube formation and emphasizes the need for deeper research into these upstream processes to uncover Autism’s developmental roots. YT video of tryptophan and microtubules https://youtu.be/AY6GmS_AePk?si=K_ZTy5RjLGkm1hGd Inner Cell Life video https://youtu.be/RrS2uROUjK4?si=DCHs927yteOZ00dW See Stuart Hameroff, Martin Picard, Michael Levin, Jack Kruse use "autism" for $25 off at https://buy.daylightcomputer.com/RYAN03139 use "autism" for 10% discount at https://getchroma.co/?ref=autism 00:00 Daylight Computer Company, use "autism" for $25 discount 04:22 tryptophan, aromatic amino acid, microtubules, mitosis; human biology, autism 04:44 tryptophan, UGG codon, methionine, SAM, MTHFR, folate, DNA methylation; upstream biology, RNA, DNA 06:04 microtubules, train tracks, mitosis, cell division, spindle, DNA separation; skin repair 06:55 tryptophan, tubulin, microtubules, mitosis, intracellular transport, cell shape; Autism research, upstream processes 9:25 Chroma Light Devices- Lights Designed for Humans, use "autism" for 10% discount 12:27 tryptophan fluorescence, mitosis, prophase, prometaphase, metaphase, anaphase, telophase, cytokinesis; microtubules, chromosome movement, cell division, tissue repair 15:58 mitosis, neural tube, embryonic development, neuron proliferation, migration; Autism, brain size, connectivity 20:33 sensory processing, hyperconnectivity, synaptic pruning, microtubules; Autism, sensory sensitivities, cortical connections 25:06 excitation-inhibition imbalance, microtubules, environmental toxins, light exposure, fertilization, blastocyst; Autism, prenatal development, cell polarity 31:09 microtubules, neural tube, gastrulation, neurogenesis, synaptogenesis, ectoderm, mesoderm, endoderm; Autism, cell migration, 37:18 outro, reviews X: https://x.com/rps47586 Hopp: https://www.hopp.bio/fromthespectrum YT: https://www.youtube.com/channel/UCGxEzLKXkjppo3nqmpXpzuA email: info.fromthespectrum@gmail.com

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  Autism, Circadian Rhythms & Protocols

  Autism, Circadian Rhythms & Protocols

  E60

  7 Aprile, 2025

  33:33

  In this episode, we navigate the fascinating world of circadian rhythms and their profound impact on our health. We cover essential biology and protocols for human health, Autism or not. We will discuss how these natural cycles of light and dark regulate our biology, from hormone production to mood and cellular function, and why disruptions—particularly from artificial light—are a growing concern in modern society. Highlighting the role of melanopsin, a blue light-absorbing protein discovered as recently as 1998, we explore how exposure to LED and tech light can throw off our internal clocks, a challenge especially relevant for those with autism who often struggle with circadian rhythm issues. Modern life has two problems: 1) removing ourselves from the full sun spectrum and 2) extending the day with artificial light at night. This, in large part, explains the origins of Autism: 1) a lack of biological energy (energy from the full sun spectrum during development- remember the episodes on neurulation, embryo and womb) and 2) improper clock-timing in our biology (in large part, this is why the gastrointestinal comorbid problem is heavily involved with Autism). We also introduce actionable protocols to reset and maintain a healthy circadian rhythm, whether you're autistic or not, emphasizing the critical role of sunlight at different times of day—morning, midday, and evening. We will discuss innovative solutions like the Daylight Computer, a blue light-free, flicker-free device designed with sensory-sensitive users in mind, and Chroma light devices that harness specific wavelengths to enhance well-being. Alongside these insights, we touch on historical and environmental factors, including a thought-provoking comparison to the Amish lifestyle, to underscore how our modern world might be influencing Autism rates and overall health. use "autism" for $25 off at https://daylightcomputer.com?sca_ref=8231379.3e0N25Wg3w use "autism" for 10% discount at https://getchroma.co/?ref=autism 00:00 Circadian rhythms introduced; blue light’s impact via melanopsin and Daylight Computer’s benefits. 00:42 Daylight Computer Company 5:00 Blue light’s harm, autism energy deficits, and artificial vs. natural light comparison. 08:01 Melanopsin’s role, modern light’s disruption, and historical autism link to artificial light. 12:01 Amish lifestyle comparison and modern environments’ effect on autism rates. 16:01 Morning sunlight protocol for circadian reset via SCN and melatonin timing. 20:01 Morning sun primacy; Non-Negotiable 21:23 Chroma light devices for health 24:33 Midday sun / UV light for longevity, evening sun’s role, and ranking sunlight importance. 28:01 Nighttime light management: avoid overhead lights, prefer candles/red lights, ensure dark sleep. 32:01 Maternal health benefits, reviews/ratings, and social media/podcast engagement X: https://x.com/rps47586 Hopp: https://www.hopp.bio/fromthespectrum YT: https://www.youtube.com/channel/UCGxEzLKXkjppo3nqmpXpzuA email: info.fromthespectrum@gmail.com

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  Dr. Richard Frye, MD, PhD: All about Leucovorin & Benefits for the Autistic Phenotype

  Dr. Richard Frye, MD, PhD: All about Leucovorin & Benefits for the Autistic Phenotype

  E59

  31 Marzo, 2025

  01:02:07

  For this episode, we discuss the roles and sensitivity of mitochondria with Dr. Richard Frye, MD, PhD. Dr. Frye received an MD and a PhD in Physiology and Biophysics from Georgetown University. He is board certified in Pediatrics, Neurology with special competence in Child Neurology, and as a Certified Principal Investigator. In addition, he has a Masters in Biomedical Sciences and Biostatistics from Drexel University. Dr. Frye has over 300 publications in leading journals and book chapters. Dr. Frye shares many figures during the conversation so the listener can follow along. Dr. Richard Frye https://drfryemdphd.com Rossingnol Medical Center Facebook https://www.facebook.com/RossignolMedicalCenter Neurological Health Foundation https://neurologicalhealth.org Healthy Child Guide https://neurologicalhealth.org/the-guide-5/ Daylight Computer Company https://daylightcomputer.com?sca_ref=8231379.3e0N25Wg3w use "autism" in the discount code for $25 coupon. This is the future of tech. Chroma Light Therapy https://getchroma.co/?ref=autism use "autism" for a 10% discount, 0:00 Dr. Richard Frye 0:58 Daylight Computer Company 5:17 Chroma Light Devices 8:27 History of Leucovorin; low risk, high reward; Folate Receptor Alpha (FRa) 10:25 Blood Brain Barrier; Folate; CSF (cerebral spinal fluid) 14:04 DNA, RNA; MTHFR (Methylenetetrahydrofolate reductase) 17:34 Cerebral Folate deficiency; BH4, Placenta & Womb 23:35 Folate deficiency & Autism 26:21 Clinical Studies & Data 29:28 Folate & Mitochondria; Cerebral Folate Antibodies; White Matter Findings (!) 34:45 Cerebral Folate deficiency & Ranges; Autistic Phenotypes: Language, Communication, & Behaviors 40:45 Language & Communication; Self-Injurious Behaviors; Hyperactivity, Agitation; Treatment duration 42:53 Folate Autoantibodies & Maternal Health & Markers 45:30 Studies & Behavioral outcomes; inflammation & thyroid findings 46:58 Neural development; Language connections, white matter tracts & distal connections 48:53 Leucovorin for different severity/levels of Autism; Spinal Bifida 51:08 Preparing for pregnancy 53:50 Transgenerational aspects of Folate Autoantibodies Research; Prenatal Care & Awareness 59:32 Guidance & Support X: https://x.com/rps47586 Hopp: https://www.hopp.bio/fromthespectrum YT: https://www.youtube.com/channel/UCGxEzLKXkjppo3nqmpXpzuA email: info.fromthespectrum@gmail.com

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  Nicole Rincon, PA-C: Various Biomarkers including Gastrointestinal Issues & Autism

  Nicole Rincon, PA-C: Various Biomarkers including Gastrointestinal Issues & Autism

  E58

  24 Marzo, 2025

  01:18:05

  Nicole Rincon https://www.nicolerincon.com Nicole's X https://x.com/NicoleRinconPA Rossignol Clinic https://rossignolmedicalcenter.com TACA Info: https://tacanow.org/wp-content/uploads/2019/10/F-H-2-Nicole-Rincon-Beginning-Biomed.pdf TACA Talks: https://www.nicolerincon.com/videos Publications https://rossignolmedicalcenter.com/articles-publications/#published-2024-2-articles Nicole Episode 1 https://www.youtube.com/watch?v=BBkdgwVfcZI Nicole Episode 2 https://www.youtube.com/watch?v=auLReV0DHkQ Daylight Computer Company https://daylightcomputer.com use "autism" in the discount code for $25 coupon. This is the future of tech. Chroma Light Therapy https://getchroma.co use "autism" for a 10% discount, ***THIS IS NOT MEDICAL ADVICE*** 0:00 Nicole Rincon 1:10 Daylight Computer Company; DC-1 5:33 Pre-pregnancy checks; Vitamin D 8:37 MTHFR, Folate; Mitochondria; CPR, ESR, Inflammation 11:12 GI; CSA; Bacteria, Fungus, Parasites, Calprotectin; Zonalin; MS & Proteus Mirabilis 13:06 Organic Acid Test (OAT); Clostridia 15:24 MTHFR; C677, 1298; Folinic Acid 19:02 Folate's role in pregnancy and development; Critical info about types and duration 22:35 Cholesterol; Maternal & Child; Speech & Communication 25:06 Telepathy; Autism Rates 26:40 Dysbiosis; PCOS 29:30 Cholesterol ranges & symptoms; mood, irritability, cognition, aggression; Cortisol & Hormones 37:02 Dysbiosis symptoms; Self-Injurious, Posturing 41:08 Identifying symptoms in Non-Verbal; Self-Injurious 45:08 Importance of Gut Health & Checks; Vitamin D, Electrical Efficiency & Biological Energy 48:17 Autistics and pale skin; too many are pale; supplementing Vitamin D, K2; Brands 51:00 Proprietary blends warning; abbreviated doses; Fungal overgrowth, Yeast 55:49 "Binders;" Magnesium 61:00 Fungal Overgrowth & Autism; OAT, Clostridia, C. diff, aggression, self-injurious; Antibiotics & Probiotics 1:05:42 Telepathy Tapes, Autism, Water (Cytochrome C Oxidase), Coherence; Luc Montagier NOT Emilio Del Giudice; Distal Connections via Water and NOT axons; Outro X: https://x.com/rps47586 Hopp: https://www.hopp.bio/fromthespectrum YT: https://www.youtube.com/channel/UCGxEzLKXkjppo3nqmpXpzuA email: info.fromthespectrum@gmail.com

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  Neurulation, Neuroepithelial Cells, & Mesencephalon

  Neurulation, Neuroepithelial Cells, & Mesencephalon

  E57

  17 Marzo, 2025

  39:19

  Why doesn't the MESENCEPHALON further subdivide into larger regions of the brain? In this episode, we will expand on the neurulation time and focus on the brain formation, spotlighting the proencephalon, mesencephalon, and rhombencephalon, which emerge around days 22–23 of embryonic life. The proencephalon (forebrain) splits into the telencephalon—think cerebral hemispheres for cognition—and the diencephalon, home to the thalamus and hypothalamus for sensory and hormonal control. Meanwhile, the rhombencephalon (hindbrain) divides into the metencephalon (pons and cerebellum, key for movement) and myelencephalon (medulla, handling [mostly] autonomic essentials like breathing). The mesencephalon stands out as a non-subdividing relay hub. The mesencephalon offers tremendous insights into the Autistic phenotype with its roles in biasing the living organism's attention to the environment. Autism and the Womb https://youtu.be/NOVp4mIroug Autism, Neurulation, & Embryogenesis https://youtu.be/TXkc93uGNuw Autism & Eye Movements https://youtu.be/1amB5e9qzg4 Autism & Sensory Processing Part 1 https://youtu.be/HPvwvtu5hB4 Autism & Sensory Processing Part 2 https://youtu.be/iWy9Rligzic Daylight Computer Company https://daylightcomputer.com use "autism" in the discount code for $25 coupon. This is the future of tech. Chroma Light Therapy https://getchroma.co use "autism" for a 10% discount, 0:00 Daylight Computer Company 04:22 Neuralation and Brain Development 05:09 Maternal Factors and Biomarkers (Tyrosine, Hypothyroidism, etc.) 06:46 Tryptophan and Its Role in Embryogenesis 08:34 Environmental Insults and Toxins 09:19 Embryogenesis and Brain Formation (Proencephalon, Mesencephalon, Rhombencephalon 10:43 Telencephalon 10:57 Diencephalon 12:34 Rhombencephalon 12:52 Metencephalon 13:35 Myelencephalon 15:12 Evolutionary Perspective of the Mesencephalon 21:39 Chroma Light Devices 24:48 Mesencephalon’s Role in Motor Control, Sensory Processing, and Autism; 27:12 Extrapyramidal motor system; Substantia Nigra, Red Nucleus 30:11 Additional Nuclei of the Midbrain; Ocular Motor Nuclei; Edingher-Westphal; Trochlear nerve 31:58 Paraaqueductal Gray (PAG), "Retard Strength" and Its Role in Pain, Behaviors and Autism; "Freezing" in Flight, Fight, & Freeze 36:00 Eye Movements; learning & Neuroplasticity; Motor Planning, Proprioception, Language and Speech 38:20 Wrap Up X: https://x.com/rps47586 Hopp: https://www.hopp.bio/fromthespectrum YT: https://www.youtube.com/channel/UCGxEzLKXkjppo3nqmpXpzuA email: info.fromthespectrum@gmail.com