The widespread controversy surrounding the PACE trial, a multi-million dollar study that initially recommended cognitive behavioral therapy (CBT) and graded exercise therapy (GET) as treatments for ME/CFS. Critics, led by advocate Alem Matthees, successfully utilized Freedom of Information requests to obtain the original data, which led to an independent re-analysis revealing significant methodological flaws and inflated recovery rates. This scientific challenge prompted the UK’s National Institute for Health and Care Excellence (NICE) to issue revised 2021 guidelines that formally abandoned CBT and GET as curative treatments. The updated medical consensus now characterizes ME/CFS as a biomedical condition rather than a psychological one, emphasizing the danger of post-exertional malaise (PEM). Current best practices focus on symptom management a ...