Can Creatine Reduce Depression?

Can Creatine Reduce Depression?

Talking With Docs Podcast by Dr. Brad Weening and Dr. Paul Zalzal
S1 Β· E48
Aug 3, 2025
06:56

Episode notes

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Is Creatine Just for Muscles? New Study Says No

Creatine is known for building strength β€” but new research shows it may also reduce symptoms of depression.

In this episode, doctors break down a study where creatine, combined with CBT (cognitive-behavioural therapy), helped improve mental health. It’s safe, accessible, and now showing promise beyond physical performance.

We cover:

  • How creatine affects brain function
  • What a recent clinical trial revealed
  • Whether creatine could support mood and therapy
  • Who might benefit and if it's safe to try

If you take creatine or are curious about mental health supplements, this is for you.

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πŸ“„ Study Reference: Sherpa NN, et al. Creatine + CBT in depression. Eur Neuropsychopharmacol. 2025;90:28–35. https://doi.org/10.1016/j.euroneuro.2024.10.004

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