Creatine Monohydrate: The Gold St...
Creatine Monohydrate: The Gold Standard Comparing Solubility and Bioavailability

Talking Healthspan by David Propst

Episode notes
  • Many creatine supplement manufacturers claim their product is superior to creatine monohydrate (CrM) because it is more soluble.
  • The sources state that solubility and bioavailability are not the same thing.
  • Creatine monohydrate is nearly 100% bioavailable, meaning almost all of the CrM consumed is absorbed and used by the body.
  • This high bioavailability is not affected by its solubility. Even if some CrM is undissolved in a glass of water, it will be absorbed by the body.
  • Manufacturers often make misleading comparisons when discussing solubility. For example, one study compared the solubility of creatine hydrochloride (Cr-HCl) to CrM at very different pH levels, misrepresenting real-world solubility.
  • The main benefit of increased solubility in alternat ... 
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Keywords
nutritioncreatine