Episode 155: Damiaan Denys - The ...

Episode 155: Damiaan Denys - The Promise of Deep Brain Stimulation

Keep Talking by Dan Riley
Jun 19, 2026
01:12:36

Episode notes

Damiaan Denys is a professor of psychiatry at the University of Amsterdam and the co-editor of "Deep Brain Stimulation: A New Frontier in Psychiatry."

------------

Keep Talking Substack

Spotify

Apple Podcasts

Social media and all episodes

------------

Support via Venmo

Support on Substack

Support on Patreon

------------

(00:00) Early Fascination With Human Nature

(02:18) Difficult Father and Survival Through Understanding People

(04:07) Boredom With Protocolized Psychiatry

(06:34) From Anti-Psychiatry to Evidence-Based Medicine

(10:01) What Psychiatry Is Supposed To Do

(12:27) Defining Mental Disorders and Cultural Relativity

(15:42) Choosing Psychiatry’s Biggest Mysteries

(18:04) Human Nature as Fundamentally Problematic

(20:07) OCD, Addiction, and Dopamine Theory

(23:41) Deep Brain Stimulation Origins

(26:08) Understanding Obsessions and Compulsions

(29:31) How Brain Stimulation Alters Brain Circuits

(33:12) Instant Personality Changes After Stimulation

(36:41) The Woman Who Cleaned Sixteen Hours Daily

(40:04) Self-Confidence as the Hidden Mechanism

(43:17) One Root Behind Many Psychiatric Disorders

(46:09) Why Deep Brain Stimulation Remains Rare

(49:22) Building a Future Around DBS Treatment

(53:06) The Three-Part DBS Treatment Team

(56:14) Depression Patient Rediscovers Music and Art

(58:47) DBS as Stimulation of the Mind

(01:01:08) Fragility, Vulnerability, and Human Connection

(01:05:18) Soul, Transcendence, and Psychedelic Experiences

(01:08:42) Leaving Academia and Returning to Human Beings

(01:11:36) Autonomy, Modern Life, and Resisting Comfort