House closes season five believing he spent the previous night with Cuddy — that she helped him detox from Vicodin and they slept together. He arrives at work sober and certain, carrying what he thinks is her lipstick. The case involves a man whose corpus callosum was surgically severed, leaving his hemispheres unable to communicate and his left hand acting on impulses his verbal mind never approved. House runs a misdirected search for pancreatic cancer before identifying clots from a damaged left atrial appendage. He announces to the hospital lobby that he and Cuddy slept together. She fires him. When he reaches for the lipstick to prove his point, it's a Vicodin bottle. The entire night was a hallucination. Both Amber and Kutner appear simultaneously. He tells Cuddy he's not okay, and Wilson drives him to a psychiatric facility where he checks  ...