In September 1982, seven people in the Chicago area died after taking Extra-Strength Tylenol capsules laced with cyanide. The victims had done nothing unusual; they reached for a trusted medicine in ordinary homes. This episode follows the first deaths, the Janus family tragedy, the public-health response, the massive recall, James Lewis's extortion conviction, the unsolved investigation, and the way one product-tampering crime changed medicine packaging, federal law, and everyday consumer trust around the world.