Medical Rewrites
Temporada 1
por Meghan Jeffres
Our medical rewrite today will be for Cast Away. The deep dives will be about dental abscesses and coral injuries. This podcast contains both plot spoilers and descriptions of medical problems found in Cast Away. Movie suggestion form: https://tinyurl.com/8pa8svey References used in this episode Microbiology of dental infections: · https://pubmed.ncbi.nlm.nih.gov/34571794/ · https://pubmed.ncbi.nlm.nih.gov/37294354/ Susceptibilities of oral pathogens https://pubmed.ncbi.nlm.nih.gov/35568274/ A beautiful review article – would be exception if the authors had cited primary literature. Clemence MA, Guerrant RL. Infections and Intoxications from the Ocean: Risks of the Shore. Microbiol Spectr. 2015 Dec;3(6). PMID: 27337286. https://pubmed.ncbi.nlm.nih.gov/27337286/ A case report that will make you think twice about romantic evenings in the ocean https://pubmed.ncbi.nlm.nih.gov/6490813/ Retrospective study comparing antibiotic regiments for treatment of Vibrio bloodstream infections. This is the best data I found on the topic. https://pubmed.ncbi.nlm.nih.gov/31188821/ Case series of Shewanella infections https://pubmed.ncbi.nlm.nih.gov/35573023/
Our medical rewrite today will be for Wolf of Wall Street, the deep dives will be about cocaine and methaqualone. Movie suggestion form: https://tinyurl.com/8pa8svey References used in this episode Cocaine and the cardiovascular system · Review https://pubmed.ncbi.nlm.nih.gov/28662796/ · Review https://pubmed.ncbi.nlm.nih.gov/21156654/ Cocaine and sexual function systematic review https://pubmed.ncbi.nlm.nih.gov/37085960/ Rat study about nitric oxide and cocaine https://pubmed.ncbi.nlm.nih.gov/9657630/ Sexual behavior and cocaine/heroin use · Survey https://pubmed.ncbi.nlm.nih.gov/20545385/ · Survey https://pubmed.ncbi.nlm.nih.gov/28471320/ Study of PD5 inhibitors and nitric oxide production https://pubmed.ncbi.nlm.nih.gov/19371941/ Methaqualone review https://pubmed.ncbi.nlm.nih.gov/36651763/
Our medical rewrite today will be for Bridesmaids. We have two deep dives today, tattoo infections and foodborne diarrhea. Please note that this podcast contains both plot spoilers and descriptions of infectious diseases found in the movie Bridesmaids. Movie suggestion form: https://tinyurl.com/8pa8svey References 2012 investigation of tattoo infections in Rochester New York: https://pubmed.ncbi.nlm.nih.gov/22913660/ 2019 investigation of tattoo infections in Miami: https://pubmed.ncbi.nlm.nih.gov/30452604/ Systematic review of tattoo infection pathogens: https://pubmed.ncbi.nlm.nih.gov/27788747/ Pharmacodynamic calculations: Cephalexin 1 g, will result in a peak of 30 mcg/mL in one hour, a 1 hour half-life, and an MIC for Strep or Staph of 4 mcg/mL, results in a percent time above MIC of around 50%. IDSA Guidelines on Infectious Diarrhea: https://pubmed.ncbi.nlm.nih.gov/29194529/ Acute diarrhea review with rehydration recipes: https://pubmed.ncbi.nlm.nih.gov/35839362/ Risks of antimotility medication after consumption of contaminated foods: https://pubmed.ncbi.nlm.nih.gov/15844055/ , https://pubmed.ncbi.nlm.nih.gov/22895383/ RCT: loperamide vs. rifaximin vs. combination: https://pubmed.ncbi.nlm.nih.gov/17382603/ TrEAT TD RCT: https://pubmed.ncbi.nlm.nih.gov/29029033/ ESBL acquisition with antibiotic and travelers diarrhea: https://pubmed.ncbi.nlm.nih.gov/25613287/ Resistance Map: https://resistancemap.onehealthtrust.org/ ESBL acquisition with loperamide and antibiotics: https://pubmed.ncbi.nlm.nih.gov/26691898/
My name is Meghan Jeffres and I am the host of Medical Rewrites where we rewrite movie scenes with evidence-based medicine. More importantly it is about redemption. On this podcast we will fix the medical plot points that keep us up and night staring at the ceiling asking – why didn’t the script writers just call me? This podcast for the clinicians that can’t help but lean over to their neighbor in the theater and whisper “That is wrong” during every medical scene. We know they don’t care, but we just can’t help it. I am an Associate Professor at the University of Colorado Skaggs School of Pharmacy on the Anschutz Medical Campus where I teach infectious diseases and clinical problem solving. I have been hospital-based internal medicine and infectious diseases pharmacist since I completed my ID residency in 2006. My research focuses are antibiotic adverse reactions, allergies, and active learning. My plan is to work my way through the list of movies, that I genuinely adore, but have medical plot points that fall short of best practices. For each movie we will identify medical issues, do a deep dive on the topic, and rewrite the scene or dialogue. I goal is to release episodes every 2 weeks. The topics covered with be 50/50 mix of ID and internal med topics. I will be bringing in experts to take us on their own deep dives and rewrites. If you have a movie that needs a rewrite. I have a Google form on the website where you can release your rage about medical plot points that are responsible for your grey hair. The Medical Rewrites podcast would not have been possible without the support of my bosses at CU – shout out to Ralph Altiere and Doug Fish. I am also standing on the shoulders of podcast giants that came before me and offered their support - Lauren Biehle, Stacy Volk, Jamie Wagner, Julie Justo, and Erin McCreary – you are all the absolute best.