This Episode examine the complex nature of sensitive skin (SS) and dermatitis, identifying them as conditions driven by a combination of genetic, neurogenic, and environmental factors. Research highlights that SS involves neurogenic inflammation and hypersensitivity of sensory nerve fibers, particularly involving TRP channels and overactive mast cells. External triggers such as pollution, UV exposure, seasonal changes, and chemical irritants in cosmetics—like preservatives and fragrances—frequently aggravate these conditions by damaging the skin barrier. Assessment methods includ ...