Episode notes
This time we take a deep dive into an hypothesis The longevity bottleneck hypothesis: Could dinosaurs have shaped ageing in present-day mammals?” by João Pedro de Magalhães
https://doi.org/10.1002/bies.202300098
See our branch of the animal kingdom, mammals, first evolved around 200 million years ago. During the age of dinosaurs. To quote the paper “long evolutionary pressure on early mammals for rapid reproduction led to the loss or inactivation of genes and pathways associated with long life”
To talk about this and look at the evolution of aging, the wonderful and fantastic Dr Molly Burke agreed to talk about her research and the science of aging more generally! Her lab at the Oregon State university uses model organisms to experimentally study evolution. (https://ib.oregonstate.edu/directory/molly-k-burke).
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