MTHFR is a real gene in the folate pathway, but it often gets treated like it explains everything. This episode keeps the scale right. You’ll learn what the enzyme does, why homocysteine became a popular lab marker, and how to separate association evidence from intervention evidence so you don’t get misled by a number moving without outcomes changing. You’ll also get a simple decision model you can use without spiraling.

You’ll learn:

• What MTHFR actually does inside folate metabolism

• Why folate was historically studied in medicine

• How homocysteine became a biomarker

• Why association studies and randomized trials tell different stories

• What DNA methylation actually means

• Why this is a pathway discussion, not a personality explanation

This episode separates evidence typ ...