The New Orleans Saints opened the 2025 NFL season with a tough Week 1 loss to the Arizona Cardinals, falling 20-13 in Kellen Moore’s debut as head coach. In this video, James Skrmetta reacts to and breaks down the Saints’ season-opening defeat, highlighting where the team came up short and what could’ve gone differently. Kyler Murray threw two touchdown passes, including a strike to rookie star Marvin Harrison Jr., as the Cardinals held off a late Saints rally. Spencer Rattler passed for 214 yards and led a last-minute drive that came up just short in the red zone, while Alvin Kamara broke free for a vintage 18-yard touchdown run. Despite a strong effort from Cameron Jordan and the Saints’ defense, costly penalties (13 for 89 yards) and missed opportunities doomed New Orleans. James recaps all the key moments, from Rattler’s near game-tying throw ...