Mission Monkeys and the Great Alphabet Rescue, follows a group of adventurous primates known as the Mission Monkeys as they embark on a quest to recover the missing letters of the alphabet. After discovering that signage and labels across their jungle home have become unreadable, the team must solve various linguistic puzzles and identify gaps in words to restore order. By working together to navigate obstacles like the Alphabet Bridge and the Missing Letter Pond, the characters demonstrate the importance of literacy and cooperation.