Medication Name/Class

• Generic/Brand: Fluphenazine / Prolixin Decanoate
• Class: First-Generation Antipsychotic (Phenothiazine)

2. Mechanism of Action

• Blocks postsynaptic D2 (dopamine) receptors in the mesolimbic system.
• Possesses weak anticholinergic and alpha1-adrenergic blocking effects.
• Strong D2 blockade reduces psychosis but directly causes extrapyramidal symptoms (EPS).

3. Expected Action/Therapeutic Effect

• Decreases dopamine neurotransmission to control psychotic symptoms.
• Provides antiemetic effects by blocking the chemoreceptor trigger zone.

4. Indications

• Priority Uses: Schizophrenia (maintenance and acute management).
• Acute agitation in psychot ...