1. Medication Name/Class

• Generic/Brand: Ziprasidone (Geodon).
• Class: Atypical Antipsychotic, Serotonin-Dopamine Antagonist (SDA).

2. Mechanism of Action

• Antagonizes dopamine D2 and serotonin 5-HT2A receptors. Modulating mesolimbic dopamine reduces positive symptoms; mesocortical serotonin modulation targets negative symptoms.

3. Expected Action/Therapeutic Effect

• Reduces positive and negative psychotic symptoms and rapidly controls acute agitation.

4. Indications

• Schizophrenia, Bipolar I (acute/maintenance), and acute agitation (IM route only).

5. Pharmacokinetics

• Absorption: PO bioavailability is ~60% b ...