Azucena Salas Ph.D. - Teasing apart the possible mechanisms behind Inflammatory Bowel Diseases with single-cell spatial transcriptomics.

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Episode notes

Ulcerative Colitis (UC) & Crohn's Disease (CD) are chronic Inflammatory Bowel Diseases that have significant effects on patients. They are notoriously hard to treat due to (but not limited to) the following reasons:

  1. Chronic and Relapsing Nature: Both UC and CD are chronic diseases that can have unpredictable and relapsing symptoms, making it difficult to maintain long-term control of the condition.

  2. The complexity of the disease: The underlying mechanisms that cause UC and CD are not fully understood, and the diseases can affect different parts of the digestive tract in different ways, making it challenging to develop a one-size-fits-all treatment approach.

  3. Inter-patient heterogeneity: People with UC and CD can have varying symptoms and respond differently to treatments, making it difficult to determ ... 

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