Muscle-Centric Medicine, a paradigm championed by Dr. Gabrielle Lyon, shifts the medical focus from managing adiposity (fat) to optimizing skeletal muscle health. This approach identifies skeletal muscle not merely as a tool for locomotion, but as the "organ of longevity" and the body’s largest endocrine organ.

The Role of Muscle in Health and Longevity

• Endocrine Function: Skeletal muscle secretes bioactive signaling molecules called myokines (e.g., IL-6, BDNF) in response to contraction. These molecules regulate inflammation, immune function, and brain health.

• Metabolic Control: Muscle is the primary site for glucose disposal and fatty acid oxidation. Healthy muscle acts as a "metabolic sink," preventing insulin resistance and type 2 diabetes. Dr. Lyon argues that many modern chronic diseases are actually symptoms of being  ...