Between 1665 and 1666, plague tore through London and killed nearly a quarter of the population in eighteen months. This episode goes far beyond the medical disaster to expose a story of weaponized bureaucracy, stark class division, and an official death toll that was deliberately undercounted. We begin with the 3,500 bodies unearthed during the Crossrail project and the 2016 DNA confirmation of the killer.

We reconstruct the overcrowded walled city and its unregulated suburbs, then examine the Searchers of the Dead, the destitute women whose plague verdicts triggered 40-day household quarantines and who could be bribed for a cup of ale to record a different cause of death. We contrast London's adversarial collapse with the village of Eyam's voluntary quarantine, and explore the modern finding that human body lice, not just rat fleas, drove ...