In 542 AD the most powerful man in the world lies covered in black tumors inside his palace in Constantinople while 10,000 people die outside every single day. Emperor Justinian survives, but his dream of a reunited Roman Empire does not. The force that defeats him is not an army but an invisible microscopic pathogen.

We trace the Plague of Justinian from its origins in the mountains of Central Asia to the grain ships of Egypt, unpacking the terrifying biology of plague transmission and the climate shock that triggered it. It is an ancient catastrophe that doubles as a blueprint of systemic fragility, with unsettling parallels to our own hyper-efficient supply chains.

• How DNA from ancient skeletons traced Yersinia pestis to the Tian Shan mountains and along nomadic migration routes
• The gruesome mechanism by which a blocke ...