This Workflow Architecture Specification v5.0, a technical framework for building modular, FDA-compliant AI systems in precision medicine. The system replaces monolithic workflows with a library of shared bricks, which are reusable sub-workflows that perform specific tasks like data normalization, genomic risk calculation, and report generation. A centralized Universal Data Envelope ensures seamless communication between components by standardizing JSON structures and maintaining a mandatory audit trail for clinical accountability. Integration with LLM-driven prompt generators and specialized databases like Supabase and Neo4j allows the platform to synthesize complex patient data into actionable clinical insights. This architecture prioritizes scalability and regulatory a ...