Today Rome sits down with a living legend: Dr. Lee Hood, CEO of Phenome Health, a trailblazer who helped launch the Human Genome Project and has spent 60+ years pushing medicine forward. This triumphant conversation shows how precision medicine—using your genome, your microbiome, your blood, and even your wearables—can predict risk early, prevent disease, and extend health span.

Dr. Hood shares how systems biology and P4 medicine (predictive, preventive, personalized, participatory) are moving us beyond “sick care” to true health care.

We dig into how blood is a “window” into the body’s organs, why multi-omic data plus AI can surface thousands of actionable steps, and how polygenic risk scores and early biomarkers can flag danger years before symptoms.

Dr. Hood explains practical wins: lowering biological age, catching metabolic ...