⚫️ “Cortical gray matter structure in boys with Klinefelter syndrome.”

Published in 2021, a study by Stanford University scientists based on neuroimaging focuses for the first time not only on differences in thickness in certain areas of the brain of Extra X males (KS) but also on brain surface variations. At the same time it avoids any testosterone treatment bias that may have skewed previous MRI neuroimaging studies, by working with non-treated prepubertal or early pubertal boys only.

This new approach seems to show more convincing correlations between KS brain variations and typical cognitive and behavioral variations than previously observed, for instance in the area of facial emotion recognition - a topic discussed in Episode 3 from the point of view of  ...