A recent article published in the Journal of Clinical Rheumatology (March 2025) highlights the importance of the innate immune response in systemic lupus erythematosus. Join me as I briefly review the innate immune system, its response in lupus, and what it means for those living with lupus and their healthcare team.

Key Takeaways:

🔹 Stat Insight: Up to 80% of lupus patients exhibit a persistent Type I interferon response, a key driver of inflammation in the disease.

🔹 Stat Insight: Elevated neutrophil extracellular traps (NETs) were detected in nearly 90% of active lupus cases, worsening disease progression.

🔹 Stat Insight: 50-60% of lupus patients with kidney involvement show low complement levels,  ...