## 🎧 Episode 82: The Brain's Chemical Seesaw ### Enticing One-Sentence Description What if ketamine doesn't relieve depression by permanently altering brain chemicals, but by forcing a stuck neural seesaw to recalibrate in real time? We dive into a landmark meta-analysis of living brain imaging studies to reveal why lasting relief is rooted in a dynamic balancing act mid-infusion—and how individual baseline chemistry could finally eliminate psychiatric guesswork. ### Engaging Description For decades, depression was blamed on a chemical deficit, but what if brain imaging has been taking snapshots at the wrong times? A landmark systematic review reveals that ketamine leaves 24-hour resting neurotransmitter levels unchanged—because its true antidepressant power is a dynamic balancing act unfolding mid-infusion. Discover how acute glutamate cycling  ...