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Betamethasone is a synthetic glucocorticoid utilized primarily for its anti-inflammatory and immunosuppressive properties. It is available in systemic forms (injectable and oral) and topical formulations, which range from medium potency, such as betamethasone valerate, to high or very high potency, such as betamethasone dipropionate.

Mechanism of Action At the cellular level, betamethasone works by inducing lipocortins, which inhibit phospholipase A2. This action prevents the breakdown of lysosomal membranes and stops the release of arachidonic acid, thereby halting the production of endogenous inflammatory mediators