Main Points - This was a multicenter randomized controlled trial comparing long-term (12 months) vs short-term (3 months) dual antiplatelet therapy (DAPT) with aspirin and clopidogrel after stent-assisted coil embolization (SACE) for cerebral aneurysms. - 142 patients were recruited and randomized. The primary outcome was ischemic stroke rate during 3-12 months after SACE. - There was no significant difference in ischemic stroke rates between the long-term and short-term DAPT groups (0 vs 2.1 per 100 person-years). - Rates of the secondary outcomes (death/any stroke, hemorrhagic events, death/stroke/hemorrhage, retreatment/stent issues) were also not significantly different between groups. - The trial was underpowered due to ...