#43: You started HRT, so why are you more puffy, more exhausted, and gaining weight?
Note sull'episodio
In this episode of Muscle, Strength and Menopause, Sara Frenza dives deep into the hidden science of estrogen metabolism and hormone clearance. As a board-certified functional medicine nutrition practitioner on HRT herself, Sara explains why HRT fails to address the root causes of weight loss resistance, fluid retention, and chronic fatigue. She breaks down how sluggish liver pathways, gut dysbiosis, high cortisol, and hidden thyroid dysfunction block hormone performance, turning your treatment into a source of frustration.
Why HRT acts as a fire alarm silencer rather than putting out the root metabolic fire causing your symptoms, Today, you'll discover the three phases of estrogen clearance (liver phase 1, phase 2 methylation, and gut phase 3) and how an overgrowth of beta-glucuronidase bacteria or constipation causes your body to recycle estrogen right back into your bloodstream. We explore why muscle loss is the single biggest driver of midlife weight gain, why HRT protects muscle but cannot build it without resistance training and optimal protein, and how high cortisol steals from your progesterone production. Finally, Sara breaks down why 20% of thyroid conversion happens in the gut and why comprehensive functional testing—including DUTCH urine testing, GI-MAP stool testing, and full blood panels—is essential to map out your unique hormone roadmap.
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