House is shot twice during a routine differential diagnosis by a man whose wife — a former patient — took her own life after House exposed her husband's affair. House wakes in the ICU two days later with his chronic leg pain mysteriously gone, then continues working a case involving grotesquely escalating symptoms: a hemorrhaging eye, a bursting scrotum, every test returning negative. When his team reveals the patient's wife he had been interrogating never existed, House realizes the ketamine administered during his surgery may have fractured his grip on reality. Each layer he tries to escape collapses into another hallucination, until he recognizes that his team — perfectly aligned with his every conclusion — can only be projections of his own subconscious. He deliberately kills the patient to break the logic of the dream, and wakes on a real gu ...