In this episode, we talk with Gašper Šolinc from the Department of Molecular Biology and Nanobiotechnology at the National Institute of Chemistry about how lipids play a surprising role in the structure and function of protein nanopores.

We explore his team’s recent Nature Communications study on the Fav protein, showing how this coral-derived nanopore interacts with over 100 lipids, including cholesterol, to stabilize its structure. These findings highlight the critical, often overlooked role of lipids in membrane protein assemblies.

From cryo-EM insights to future applications in biosensing, this conversation bridges molecular biology, nanotechnology, and synthetic bioengineering.

🔬 Read the study: https://www.nature.com/artic ...