30 Day FDA Drug Development in Cannabinoid and Psychedelic Spaces - Day 26 Advanced Topics in Process Chemistry and Scalability
Cannabinoid and Psychedelic Pharmacology and Drug Developmen... di Jim Mitchell and Google NotebookLM
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This podcast episode explores the complex challenges of scaling up production of cannabinoid and psychedelic APIs (Active Pharmaceutical Ingredients) from laboratory to commercial scale. Using Watson's Pharmaceutical Process Development as a guide, the discussion covers key aspects including:
- Balancing yield maximization, cost minimization, and waste management while maintaining product safety and efficacy
- The differences between batch and continuous processing methods
- Specific challenges with sensitive compounds from natural sources, including quality control and contamination prevention
- Environmental considerations and sustainable production methods, including green chemistry approaches
The episode provides detailed insights into both traditional extraction methods and emerging synthetic approaches for prod ...