Join us in this fascinating episode with Dr. Hawn as we delve into the realm of psychopathology, biological aging, and mortality. Psychopathology is often linked to faster biological aging and premature death. Dr. Hawn and her team's pioneering research have sought to better understand these relationships. They have examined associations between broad dimensions of psychopathology, post-traumatic stress disorder (PTSD), and GrimAge, a DNA methylation biomarker indicative of mortality risk relative to age. The research has also focused on understanding the neurobiological correlates of GrimAge, including neurocognitive functioning, inflammation, neuropathology, metabolic disease, and cortical thickness. Their findings show that externalizing psychopathology significantly predicts GrimAge, while PTSD appears to be linked to GrimAge in younger but n ...