Join us in this fascinating episode where we converse with Dr. Thomas Armbruster on his innovative research in neurobiology. The episode dives deep into the intricacies of astrocyte-neuron interactions and the unique role that astrocytes play in neuronal activity.

Astrocytes, a type of glial cell, are known to interact with neuronal synapses through their distal processes, aiding in the removal of glutamate and potassium (K+) post-neuronal activity. These actions are dependent on astrocyte membrane potential (Vm). Interestingly, while astrocyte Vm has long been considered largely static, Dr. Armbruster’s research paints a different picture.

By utilizing genetically encoded voltage indicators, Dr. Armbruster's team measured Vm at peripheral astrocyte processes (PAPs) in mice. They discovered large, quick, focal, and pathway-specific de ...