Shining New Light on Chiral Molec...
Shining New Light on Chiral Molecules: Innovations in CPL Bio-Imaging with Dr. MacKenzie
Science Society di Dr. Catarina Cunha and co-host Victoria Wills
3 apr 2022
01:38:05
Note sull'episodio

Today, we delve into a groundbreaking frontier in bio-imaging with Dr. MacKenzie, who is pioneering methods to observe and understand the world of chiral molecular interactions – an area that, up to now, was challenging to visualize.

The Significance of Chirality:

Life's molecular machinery relies on chiral building blocks, yet monitoring these in live cells remained elusive.

Luminescent chiral molecules provide a unique optical signature, shedding light on the environment, shape, and binding state.

Introducing the CPL Laser Scanning Confocal Microscope (CPL-LSCM):

This revolutionary device can capture chiroptical contrast in live-cell imaging of both natural and designed CPL-active cellular probes.

Achievements also include the success of using two-photon excitation, fully restoring the CPL spectrum in the pro ... 

Parole chiave
2pe cpl spectroscopy
diffraction limited enantioselective chiral contrast imaging
chirality
molecular machinery
two photon excitation
emissive chiral probes
distinct enantiomers
chiral europium complex
bioimaging
chiral building blocks