Ryan and Clinton return for another picks episode as the weekend we have all been waiting for has arrived. A mammoth weekend nationally is highlighted in the Big Ten with three top-5 teams facing their toughest tests to date, as Ohio State/Oregon and Penn State/USC square off. How do the guys see these two shaking out? Elsewhere in the slate, Washington looks to avoid a letdown with a sleeping noon kickoff at Iowa, Wisconsin looks to prove last week was no fluke against Rutgers, while Minnesota looks to complete its LA conquest at the Rose Bowl against UCLA.

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