Hormone Pellets: Benefits, FDA Warnings, Side Effects & What ACOG Says | Funny Medicine

On the Funny Medicine podcast, Yvy and Julie return to discuss hormone pellets, a controversial wellness trend popular on social media and in cities like Miami. They explain what pellets are, how they’re implanted under the skin for 3–6 months, and why the inability to remove or titrate dosing drives major medical concerns. They review the history of pellets from 1930s research, contrast pellets with standard hormone replacement therapy, and describe how perimenopause/menopause symptoms and the 2002 WHI backlash contributed to demand. They cite studies showing supraphysiologic hormone levels with pellets, higher side-effect rates than FDA-approved therapy, and FDA/NASEM concerns including thousands of unreported adverse events. They summarize posit ...