Hannah Mamuszka and Lena Chaihorsky interview Kristine Ashcraft, a molecular biologist who has worked in pharmacogenomics (PGx) since 2000, first at Genelex, one of the earliest labs to offer the testing, and later as founder of the clinical-decision-support tool YouScript. Ashcraft traces the field's slow adoption despite strong evidence, explaining how most people carry gene variants affecting how they metabolize common drugs, using a "liver highway" analogy: some people have fewer or more "lanes" (enzyme activity), and drugs, foods, and other medications can shut lanes down. YouScript's clinical studies showed large reductions in hospitalizations, ER visits, and deaths, and the European PREPARE trial's 30% drop in adverse drug reactions. A recurring theme is misaligned incentives — she describes a hospital CFO explaining they make money from t ...