This episode features Samuel Martinelli, chair of the International Insecticide Resistance Action Committee (IRAC), who presented IRAC's history, key achievements, and future directions. IRAC has become the global authority on mode of action (MoA) classification for insecticides, developing the widely recognized classification system and guidelines that help farmers and advisors manage pesticide resistance. The discussion highlights IRAC's three pillars (MoA classification, guidance/tools development, and global coordination) and outlined their next major initiative: creating a comprehensive resistance database to provide validated, publicly available intelligence on insecticide resistance developments worldwide.