PHARM | 1st Gen Cephalosporins (Cephalexin)
STAT Stitch Deep Dive Podcast Beyond The Bedside por Regular Guy
Notas del episodio
This is everything 1st Gen Ceph Drugs. For my RN Program this class includes Cephalexin.
First-Generation Cephalosporins
Examples: Cefadroxil, Cefazolin, Cephalexin Class: Anti-infective | Pharmacologic: Cephalosporin (1st Gen) MOA: Binds to bacterial cell-wall membrane → cell death (bactericidal).
Top Indications
1️⃣ Skin & soft-tissue infections. 2️⃣ UTIs. 💉 Cefazolin: peri-operative surgical prophylaxis.
Therapeutic Effect
Resolution of infection — ↓ redness, swelling, discharge, pain, fever.
Contraindications / Cautions
- Allergy: Cephalosporin or serious PCN reaction → risk of anaphylaxis.
- Rena ...
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