Join us in this episode with Dr. Bleris as we dive into the fascinating world of genetic, physical unclonable functions (PUFs) in human cells. PUFs are physical entities that provide a unique and irreproducible identifier for the artifact in which they are embedded. Originally popularized by the electronics industry, PUFs use the inherent physical variations of semiconductor manufacturing to establish intrinsic security measures for attesting integrated circuits.

Inspired by silicon PUFs, Dr. Bleris and his team have embarked on the creation of the first generation of genetic PUFs in human cells. These PUFs are shown to be robust, unique, and unclonable, making them virtually impossible to replicate. Moreover, the team's groundbreaking work with CRISPR-engineered PUFs (CRISPR-PUFs) opens new possibilities for establishing provenance attesta ...